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Approach toAIDS vaccineshows hopein monkeys
AIDS researchers reported Monday they had designed a
vaccine that they believe may do what no other vaccine has
done before — protect people from infection with the virus. So
far the team at the Institute of Virology at the University of
Maryland in the U.S. has only tested monkeys. And they note
that people trying to design a vaccine against the AIDS virus
have repeatedly failed. But they think their design, based on
the mechanism the virus uses to attach to the immune cells it
targets, is the best yet. “In several animals, including
monkeys, we were able to generate neutralizing antibodies that
are not type-specific but broadly cover various types of HIV,”
Dr. Robert Gallo, who helped discover the AIDS virus and who
heads the institute where the work was done, said in a
telephone interview. Making a vaccine against HIV is difficult
because the virus integrates itself into cells, and because it
attacks the very immune cells that are normally stimulated by
a vaccine. Although dozens of vaccines are in various stages
of development, no one thinks a truly protective vaccine has
been designed. At best, doctors now hope that one or more of
the vaccines may simply help people to live a little longer
with the virus, or perhaps to reduce the ease with which it is
transmitted from person to person. (SD-Agencies)
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